TY - JOUR
AU - Jelte van der Vaart
AU - Mart M. Lamers
AU - Bart L. Haagmans
AU - Hans Clevers
AB - The COVID-19 pandemic has emphasised the need to develop effective treatments to combat emerging viruses. Model systems that poorly represent a virus' cellular environment, however, may impede research and waste resources. Collaborations between cell biologists and virologists have led to the rapid development of representative organoid model systems to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We believe that lung organoids, in particular, have advanced our understanding of SARS-CoV-2 pathogenesis, and have laid a foundation to study future pandemic viruses and develop effective treatments.
BT - Disease Models & Mechanisms
DA - 2021-06-28
DO - 10.1242/dmm.049060
IS - 6
N2 - The COVID-19 pandemic has emphasised the need to develop effective treatments to combat emerging viruses. Model systems that poorly represent a virus' cellular environment, however, may impede research and waste resources. Collaborations between cell biologists and virologists have led to the rapid development of representative organoid model systems to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We believe that lung organoids, in particular, have advanced our understanding of SARS-CoV-2 pathogenesis, and have laid a foundation to study future pandemic viruses and develop effective treatments.
PY - 2021
EP - dmm049060
T2 - Disease Models & Mechanisms
TI - Advancing lung organoids for COVID-19 research
UR - https://doi.org/10.1242/dmm.049060
VL - 14
Y2 - 2023-08-09
SN - 1754-8403
ER -