TY - JOUR
KW - biomaterials
KW - Pharmacology
KW - Preclinical research
AU - Partho Protim Adhikary
AU - Qurrat Ul Ain
AU - Andreas Christian Hocke
AU - Sarah Hedtrich
AB - Scientists worldwide struggle to identify suitable animal models to study SARS-CoV-2 infections. Interspecies-related differences, such as host specificity, divergent immune responses, or the unavailability of species-specific reagents hamper the research. Human-based models, such as micro-engineered multi-organs-on-chip, may hold the solution.
BT - Nature Reviews Materials
DA - 2021-05
DO - 10.1038/s41578-021-00305-z
IS - 5
LA - en
N2 - Scientists worldwide struggle to identify suitable animal models to study SARS-CoV-2 infections. Interspecies-related differences, such as host specificity, divergent immune responses, or the unavailability of species-specific reagents hamper the research. Human-based models, such as micro-engineered multi-organs-on-chip, may hold the solution.
PY - 2021
SP - 374
EP - 376
T2 - Nature Reviews Materials
TI - COVID-19 highlights the model dilemma in biomedical research
UR - https://www.nature.com/articles/s41578-021-00305-z
VL - 6
Y2 - 2023-08-09
SN - 2058-8437
ER -