TY - JOUR
KW - body-on-a-chip
KW - Disease modelling
KW - drug testing
KW - Human Body
KW - Humans
KW - Lab-On-A-Chip Devices
KW - Microfluidic device
KW - organ-on-a-chip
KW - Patient-on-a-chip
KW - Precision Medicine
KW - Precision Medicine
KW - Stem cell
AU - Zhong Alan Li
AU - Rocky S. Tuan
AB - Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically linked OoCs. Herein, the major innovations in their BoC system are discussed, followed by our future perspectives on enhancing the physiological relevance and scalability of BoCs for applications in studying disease mechanisms, testing potential therapeutics, and developing personalized medicine.
BT - Stem Cell Research & Therapy
DA - 2022-08-20
DO - 10.1186/s13287-022-03130-5
IS - 1
LA - eng
N2 - Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically linked OoCs. Herein, the major innovations in their BoC system are discussed, followed by our future perspectives on enhancing the physiological relevance and scalability of BoCs for applications in studying disease mechanisms, testing potential therapeutics, and developing personalized medicine.
PY - 2022
EP - 431
T2 - Stem Cell Research & Therapy
TI - Towards establishing human body-on-a-chip systems
VL - 13
SN - 1757-6512
ER -