00360nas a2200121   4500000000100000000000100001000000100002008004100003260001500044100003600059245004100095856010200136       2023                            d  c2023-11-141 aU.S. Food & Drug Administration00aAdvancing Alternative Methods at FDA  uhttps://www.fda.gov/science-research/about-science-research-fda/advancing-alternative-methods-fda