00843nas a2200205   4500000000100000000000100001008004100002260001500043653001800058653002200076653001800098653002300116100001500139700002400154245005300178856005500231300000800286520032900294022001400623       2024                            d  c2024-10-3010aAssay systems10aBiological models10aLab-on-a-chip10aTissue engineering1 aYaqi Sheng1 aYan Yan Shery Huang00aCryopreservation of in vitro human tissue models  uhttps://www.nature.com/articles/s44222-024-00261-7  a1-33 aThe widespread use and translation of engineered in vitro tissues, such as organoids, organ-on-chip devices and microphysiological models, will require designs that can be preserved by cryopreservation. Here, we outline the factors that affect their cryopreservation, highlighting the challenges that remain to be addressed.  a2731-6092