03010nas a2200301   4500000000100000000000100001008004100002260001500043653001900058653001500077653001500092653002100107653002300128653003500151653002300186653001900209100002400228700001900252700002000271700002100291700002600312700002300338245016800361856006600529490000600595520209300601022001402694       2020                            d  c2020-03-0510aanimal welfare10aEnrichment10aEuthanasia10aWorkplace stress10acompassion fatigue10ahuman-animal interaction (HAI)10aLaboratory animals10asocial support1 aMegan R. LaFollette1 aMegan C. Riley1 aSylvie Cloutier1 aColleen M. Brady1 aMarguerite E. O'Haire1 aBrianna N. Gaskill00aLaboratory Animal Welfare Meets Human Welfare: A Cross-Sectional Study of Professional Quality of Life, Including Compassion Fatigue in Laboratory Animal Personnel  uhttps://www.frontiersin.org/articles/10.3389/fvets.2020.001140 v73 aLaboratory animal personnel may experience significant stress from working with animals in scientific research. Workplace stress can be assessed by evaluating professional quality of life, which is comprised of compassion fatigue (i.e., burnout and secondary traumatic stress) and compassion satisfaction. This research aimed to explore the associations between risk factors and professional quality of life in laboratory animal personnel. In a cross-sectional, convenience sample design, laboratory animal personnel were recruited from widespread online promotion. A total of 801 personnel in the United States or Canada completed an online survey regarding professional quality of life, social support, euthanasia, enrichment, stress/pain levels, and human-animal interactions. Participants worked in a wide range of settings (e.g., industry, academia), research types (e.g., basic, applied, regulatory), species (e.g., non-human primates, mice), and roles (e.g. animal caretaker, veterinarian). Data were analyzed using general linear models. Personnel who reported higher compassion fatigue also reported lower social support, higher animal stress/pain, higher desire to implement more enrichment, and less control over performing euthanasia (p’s0.05). Our findings show that the professional quality of life of laboratory animal personnel is associated with several factors. Personnel reporting poorer professional quality of life also reported less social support, higher animal stress/pain, less enrichment diversity/frequency and wished they could provide more enrichment, using physical euthanasia, and less control over performing euthanasia. Poorer professional quality of life was also seen in personnel working as trainers, at universities, and longer hours. This study contributes important empirical data that may provide guidance for developing interventions (e.g., improved social support, decreased animal stress, increased animal enrichment diversity/frequency, greater control over euthanasia) to improve laboratory animal personnel’s professional quality of life.  a2297-1769