02042nas a2200385   4500000000100000000000100001008004100002260001200043100001200055700001700067700001900084700002100103700001800124700001900142700001600161700001900177700002000196700002100216700001500237700001700252700001600269700001900285700002100304700002300325700001800348700002100366700001900387700002300406245002800429856004800457300001100505490000700516520111900523022001401642       2020                            d  c2020-021 aWei Sun1 aBinil Starly1 aAndrew C. Daly1 aJason A. Burdick1 aJürgen Groll1 aGregor Skeldon1 aWenmiao Shu1 aYasuyuki Sakai1 aMarie Shinohara1 aMasaki Nishikawa1 aJinah Jang1 aDong-Woo Cho1 aMinghao Nie1 aShoji Takeuchi1 aSerge Ostrovidov1 aAli Khademhosseini1 aRoger D. Kamm1 aVladimir Mironov1 aLorenzo Moroni1 aIbrahim T. Ozbolat00aThe bioprinting roadmap  uhttps://dx.doi.org/10.1088/1758-5090/ab5158  a0220020 v123 aThis bioprinting roadmap features salient advances in selected applications of the technique and highlights the status of current developments and challenges, as well as envisioned advances in science and technology, to address the challenges to the young and evolving technique. The topics covered in this roadmap encompass the broad spectrum of bioprinting; from cell expansion and novel bioink development to cell/stem cell printing, from organoid-based tissue organization to bioprinting of human-scale tissue structures, and from building cell/tissue/organ-on-a-chip to biomanufacturing of multicellular engineered living systems. The emerging application of printing-in-space and an overview of bioprinting technologies are also included in this roadmap. Due to the rapid pace of methodological advancements in bioprinting techniques and wide-ranging applications, the direction in which the field should advance is not immediately clear. This bioprinting roadmap addresses this unmet need by providing a comprehensive summary and recommendations useful to experienced researchers and newcomers to the field.  a1758-5090