01315nas a2200349   4500000000100000000000100001008004100002260001500043653001300058653003700071653003300108653001400141653002000155653002100175653003200196653001800228100003000246700001700276700002400293700002600317700002600343700001800369700001900387700001800406700001800424245007100442856008200513300001300595490000700608520033600615022001400951       2021                            d  c2021-08-0910aCOVID 1910aInstitutional funding of science10aMedicine and Health Sciences10aPandemics10aResearch ethics10aResearch funding10aTuberculosis drug discovery10aVirus testing1 aBastian Greshake Tzovaras1 aMichael Rera1 aEdwin H. Wintermute1 aKatharina Kloppenborg1 aJuliette Ferry-Danini1 aGuy Aidelberg1 aRachel Aronoff1 aAriel Lindner1 aDusan Misevic00aEmpowering grassroots innovation to accelerate biomedical research  uhttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001349  ae30013490 v193 aThe purpose of biomedicine is to serve society, yet its hierarchical and closed structure excludes many citizens from the process of innovation. We propose a collection of reforms to better integrate citizens within the research community, reimagining biomedicine as more participatory, inclusive, and responsive to societal needs.  a1545-7885