01435nas a2200205   4500000000100000008004100001260001500042653002400057653002100081653003900102653002100141653003800162100001700200245011200217856004300329300000700372490000600379520083000385022001401215       2011                            d  c2011-06-0710aAcademic Misconduct10aAlimentary Canal10aCentral Institutional Review Board10aCricoid Pressure10aEuropean Public Assessment Report1 aMark J. Rice00aThe institutional review board is an impediment to human research: the result is more animal-based research  uhttps://doi.org/10.1186/1747-5341-6-12  a120 v63 aBiomedical research today can be generally classified as human-based or nonhuman animal-based, each with separate and distinct review boards that must approve research protocols. Researchers wishing to work with humans or human tissues have become frustrated by the required burdensome approval panel, the Institutional Review Board. However, scientists have found it is much easier to work with the animal-based research review board, the Institutional Animal Care and Use Committee. Consequently, animals are used for investigations even when scientists believe these studies should be performed with humans or human tissue. This situation deserves attention from society and more specifically the animal protection and patient advocate communities, as neither patients nor animals are well served by the present situation.  a1747-5341