01237nas a2200217   4500000000100000000000100001008004100002260001500043653001900058653002000077653003800097653001200135100001500147700002300162245009900185856004700284300001200331490000700343520065500350022001401005       2020                            d  c2020-08-0110aKidney failure10aorgan-on-a-chip10aSevere acute respiratory syndrome10abioMEMS1 aHolly Ryan1 aChelsey S. Simmons00aPotential Applications of Microfluidics to Acute Kidney Injury Associated with Viral Infection  uhttps://doi.org/10.1007/s12195-020-00649-6  a305-3110 v133 aThe kidneys are susceptible to adverse effects from many diseases, including several that are not tissue-specific. Acute kidney injury is a common complication of systemic diseases such as diabetes, lupus, and certain infections including the novel coronavirus (SARS-CoV-2). Microfluidic devices are an attractive option for disease modeling, offering the opportunity to utilize human cells, control experimental and environmental conditions, and combine with other on-chip devices. For researchers with expertise in microfluidics, this brief perspective highlights potential applications of such devices to studying SARS-CoV-2-induced kidney injury.  a1865-5033