01074nas a2200181 4500000000100000008004100001260001500042100002400057700001900081700002100100700001700121245005100138856003900189300001400228490000700242520062900249022001400878 2021 d c2021-06-281 aJelte van der Vaart1 aMart M. Lamers1 aBart L. Haagmans1 aHans Clevers00aAdvancing lung organoids for COVID-19 research uhttps://doi.org/10.1242/dmm.049060 admm0490600 v143 aThe COVID-19 pandemic has emphasised the need to develop effective treatments to combat emerging viruses. Model systems that poorly represent a virus' cellular environment, however, may impede research and waste resources. Collaborations between cell biologists and virologists have led to the rapid development of representative organoid model systems to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We believe that lung organoids, in particular, have advanced our understanding of SARS-CoV-2 pathogenesis, and have laid a foundation to study future pandemic viruses and develop effective treatments. a1754-8403