01174nas a2200349   4500000000100000000000100001008004100002260001500043653002400058653003000082653001400112653000900126653002200135653000900157653001100166653002800177653002300205653001700228653001300245653001500258653001400273653001900287653002100306653002300327100001900350700002300369245007300392300001400465490000800479520032300487022001400810       2021                            d  c2021-05-1310aBiomedical Research10aBlack or African American10aCell Line10aGWAS10aGenetic Variation10aHeLa10aHumans10aPharmacogenomic Testing10aPrecision Medicine10aWhite People10aancestry10acell lines10adiversity10aDrug Discovery10apharmacogenomics10aPrecision Medicine1 aSophie Zaaijer1 aAmanda Capes-Davis00aAncestry matters: Building inclusivity into preclinical study design  a2525-25310 v1843 aHuman cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable and widely translatable. We lay out practical actions that can be taken to improve inclusivity in study design.  a1097-4172