01452nas a2200241   4500000000100000000000100001008004100002260001200043653002000055653003200075653002000107100002000127700002000147700002200167700002000189700001900209245004600228856016700274300001000441490000700451520072700458022002501185       2022                            d  c2022/0110aanimal subjects10amorally defensible research10aResearch ethics1 aHope Ferdowsian1 aAgustin Fuentes1 aL. Syd M. Johnson1 aBarbara J. King1 aJessica Pierce00aToward an Anti-Maleficent Research Agenda  uhttps://www.cambridge.org/core/journals/cambridge-quarterly-of-healthcare-ethics/article/toward-an-antimaleficent-research-agenda/A19530167CE1D088C969A6A63DE234D6  a54-580 v313 aImportant advances in biomedical and behavioral research ethics have occurred over the past few decades, many of them centered on identifying and eliminating significant harms to human subjects of research. Comprehensive attention has not been paid to the totality of harms experienced by animal subjects, although scientific and moral progress require explicit appraisal of these harms. Science is a public good and the prioritizing within, conduct of, generation of, and application of research must soundly address questions about which research is morally defensible and valuable enough to support through funding, publication, tenure, and promotion. Likewise, educational pathways of re-imagined science are critical.  a0963-1801, 1469-2147