01777nas a2200265   4500000000100000008004100001260000900042100001800051700001800069700001600087700001500103700002600118700001900144700001500163700002400178700001500202700001900217700001600236700001900252245011500271856006400386300001200450490000700462520104200469       2005                            d  c20051 aSandra Coecke1 aMichael Balls1 aGerard Bowe1 aJohn Davis1 aGerhard Gstraunthaler1 aThomas Hartung1 aRobert Hay1 aOtto-Wilhelm Merten1 aAnna Price1 aMartin Leonard1 aGlyn Stacey1 aWilliam Stokes00aGuidance on Good Cell Culture Practice - A report of the second ECVAM task force on Good Cell Culture Practice  uhttps://journals.sagepub.com/doi/10.1177/026119290503300313  a261-2870 v333 aThe maintenance of high standards is fundamental to all good scientific practice, and is essential for maximising the reproducibility, reliability, credibility, acceptance and proper application of any results produced. The aim of this Guidance on Good Cell Culture Practice (GCCP) is to promote the maintenance of these standards and to reduce uncertainty in the development and application of animal and human cell and tissue culture procedures and products, by encouraging greater international harmonisation, rationalisation and standardisation of laboratory practices, quality control systems, safety procedures, recording and reporting, and compliance with laws, regulations and ethical principles. The scope of the document has deliberately been broadly defined, to include systems based on cells and tissues obtained from humans and animals, and issues related to the characterisation and maintenance of essential characteristics, as well as quality assurance, recording and reporting, safety, education and training, and ethics.