@article{4566,
  keywords = {Cell biology, induced pluripotent stem cells, Parkinson's disease, Stem-cell biotechnology},
  author = {Xin Cui and Xinwei Li and Huimin Zheng and Yun Su and Shuyu Zhang and Mengjie Li and Xiaoyan Hao and Shuo Zhang and Zhengwei Hu and Zongping Xia and Changhe Shi and Yuming Xu and Chengyuan Mao},
  title = {Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration},
  abstract = {Parkinson’s disease (PD) is a neurodegenerative disorder marked by the loss of dopaminergic neurons in the substantia nigra. Despite progress, the pathogenesis remains unclear. Human midbrain organoids (hMLOs) have emerged as a promising model for studying PD, drug screening, and potential treatments. This review discusses the development of hMLOs, their application in PD research, and current challenges in organoid construction, highlighting possible optimization strategies.},
  year = {2024},
  journal = {npj Parkinson's Disease},
  volume = {10},
  pages = {1-14},
  month = {2024-10-20},
  issn = {2373-8057},
  url = {https://www.nature.com/articles/s41531-024-00799-8},
  doi = {10.1038/s41531-024-00799-8},
  language = {en},
}