@article{2461, author = {Robert Jordan and Stephanie L Ford-Scheimer and Rodolfo M Alarcon and Anthony Atala and Jeffrey T Borenstein and Kyle R Brimacombe and Sara Cherry and Hans Clevers and Mindy I Davis and Simon G P Funnell and Lee Gehrke and Linda G Griffith and Abigail C Grossman and Thomas Hartung and Donald E Ingber and Nicole C Kleinstreuer and Calvin J Kuo and Emily M Lee and Christine L Mummery and Thames E Pickett and Sasirekha Ramani and Edwin A Rosado-Olivieri and Evi B Struble and Zhengpeng Wan and Mark S Williams and Matthew D Hall and Marc Ferrer and Sarine Markossian}, title = {Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development}, abstract = {The National Center for Advancing Translational Sciences (NCATS) Assay Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development, held virtually on 7–8 June 2022, provided comprehensive coverage of critical concepts intended to help scientists establish robust, reproducible, and scalable 3D tissue models to study viruses with pandemic potential. This workshop was organized by NCATS, the National Institute of Allergy and Infectious Diseases, and the Bill and Melinda Gates Foundation. During the workshop, scientific experts from academia, industry, and government provided an overview of 3D tissue models’ utility and limitations, use of existing 3D tissue models for antiviral drug development, practical advice, best practices, and case studies about the application of available 3D tissue models to infectious disease modeling. This report includes a summary of each workshop session as well as a discussion of perspectives and challenges related to the use of 3D tissues in antiviral drug discovery.}, year = {2023}, journal = {The Journal of Infectious Diseases}, pages = {jiad334}, month = {2023-09-05}, issn = {0022-1899}, url = {https://doi.org/10.1093/infdis/jiad334}, doi = {10.1093/infdis/jiad334}, }