@article{1711,
  keywords = {induced pluripotent stem cells, SARS-CoV-2, Stem-cell biotechnology},
  author = {Kevin G. Chen and Kyeyoon Park and Jason R. Spence},
  title = {Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids},
  abstract = {Clinical management of patients with severe complications of COVID-19 has been hindered by a lack of effective drugs and a failure to capture the extensive heterogeneity of the disease with conventional methods. Here we review the emerging roles of complex organoids in the study of SARS-CoV-2 infection, modelling of COVID-19 disease pathology and in drug, antibody and vaccine development. We discuss opportunities for COVID-19 research and remaining challenges in the application of organoids.},
  year = {2021},
  journal = {Nature Cell Biology},
  volume = {23},
  pages = {822-833},
  month = {2021-08},
  issn = {1476-4679},
  url = {https://www.nature.com/articles/s41556-021-00721-x},
  doi = {10.1038/s41556-021-00721-x},
  language = {en},
}