@article{1191, keywords = {Biomedical Research, Black or African American, Cell Line, GWAS, Genetic Variation, HeLa, Humans, Pharmacogenomic Testing, Precision Medicine, White People, ancestry, cell lines, diversity, Drug Discovery, pharmacogenomics, Precision Medicine}, author = {Sophie Zaaijer and Amanda Capes-Davis}, title = {Ancestry matters: Building inclusivity into preclinical study design}, abstract = {Human cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable and widely translatable. We lay out practical actions that can be taken to improve inclusivity in study design.}, year = {2021}, journal = {Cell}, volume = {184}, pages = {2525-2531}, month = {2021-05-13}, issn = {1097-4172}, doi = {10.1016/j.cell.2021.03.041}, language = {eng}, }